Technical Data
D3800-03A
DLX3 (Homeobox Protein DLX-3)
Description:
The distal-less homeobox 3 (DLX3) protein is a putative transcriptional activator that has been implicated during development and differentiation of epithelial tissues. This is a homeodomain transcription factor in vertebrates, related to Distal-less in Drosophila, which is expressed in differentiating epidermal cells, in neural crest, hair follicles, dental epithelium, mesenchyme, the optic and olfactory placodes, limb bud, placenta, and in the cement gland, which is located in the extreme anterior neural plate in Xenopus embryos.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 2-4ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
NIH 3T3

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to aa220-270 of DLX3.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:
Recognizes DLX3. Species Crossreactivity: chimpanzee, bovine, canine, equine, mouse. Species sequence homology: rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bryan, J.T. et al. J. of Cell Sci. 113:4013-4023 (2000). 2. Fuchs, E. et al. Curr. Opin. Genet. Dev. 4:725-736 (1994).