		Technical Data
D7795-51	DLC-1 (Rho GTPase-activating Protein 7, Deleted in Liver Cancer 1 Protein, HP Protein, Rho-type GTPase-activating Protein 7, START Domain-containing Protein 12, StARD12, StAR-related Lipid Transfer Protein 12, DLC1, ARHGAP7, KIAA1723, STARD12)

Description:
Functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Immunohistochemistry (Paraffin): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to SVAIRKRSWEEHC, from human DLC1, at N-terminal (NP_872584.2, NP_079043.3).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human DLC1. Species sequence homology: Mouse and porcine.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Ko FC, Yeung YS, Wong CM, Chan LK, Poon RT, Ng IO, Yam JW. Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma. Liver Int. 2010 Jan;30(1):139-48.