Technical Data
Dipeptidyl Peptidase 10 (DPP10)
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma.

Suitable for use in Western Blot. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:500-1:000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgG Affinity Purified
100ug4C (-20C Glycerol)Blue IceHumanRabbit
Residues 521-539 LKEAILKKKIGKPEIKILH of human DPP10.
Purified by immunoaffinity chromatography.
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Recognizes residues 521-539 LKEAILKKKIGKPEIKILH of human DPP10.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Allen, M. et al. Nat. Genet. 2003 Nov;35(3):258-63.