Technical Data
F0030-16V
Feline Leukemia Virus, gp70 (FeLV)
Description:
The feline leukemia virus (FeLV) is the causative agent of the most important fatal infectious disease complex of domestic cats today. It is an RNA virus belonging to the family Retroviridae. FeLV can be transmitted between infected cats when the transfer of saliva or nasal secretions is involved. If not defeated by the animals immune system, the virus can be lethal.

Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry (frozen and paraffin), Immunoprecipitation, and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2b10C222Affinity Purified
SizeStorageShippingSourceHost
250ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Feline Leukemia Virus gp70
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Specificity:
Recognizes the gp85/gp70 envelope glycoprotein of feline leukemia virus. Specifically recognizes the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL). Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Grant, C.K. et al. (1983) Feline leukaemia virus envelope gp70 of subgroups B anc C defined by monoclonal antibodies with cytotoxic and effector functions. J. Immunol. 131: 3042-3048.