Fibrinogen is a 340kD soluble plasma glycoprotein which is synthesized by the liver. Fibrinogen is an inactive zymogen which is activated by thrombin in the coagulation cascade to form fibrin, the most abundant component of blood clots .Fibrinogen activation is also involved in cellular and matrix interactions, the inflammatory response, cardiovascular disease and neoplasia.
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Immunohistochemistry (Frozen): 1:5-1:50
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.
|Purified by affinity chromatography.|
|Supplied as a liquid in PBS, pH 7.4, 0.01% thimeorsal. Labeled with horseradish peroxidase (HRP).|
|Recognizes human fibrinogen. Species Crossreactivity: mouse and rat|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
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