		Technical Data
F5279-25B	FLVCR (Feline Leukemia Virus Subgroup C Receptor-related Protein 1, Feline Leukemia Virus Subgroup C Receptor, hFLVCR, FLVCR1)

Description:
FLVCR is responsible for exporting cytoplasmic heme. It may be required to protect developing erythroid cells from heme toxicity. It causes suceptibility to FeLV-C in vitro.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to C-KTVMLSKQSESAI, from human FLVCR1, at C-terminal (NP_054772.1).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human FLVCR1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Rey MA, Duffy SP, Brown JK, Kennedy JA, Dick JE, Dror Y, Tailor CS. Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis. Haematologica 2008 Nov;93(11):1617-26. Epub 2008 Sep 24.