Technical Data
J8010-01C6
Junctional Adhesion Molecule 2 (JAM 2, JAM2, JAM-2, C21orf43, CD322, CD322 Antigen, JAM IT/VE JAM, Junction Adhesion Molecule B, JAM B, JAMB, JAM-B, PRO245, Vascular Endothelial Junction Associated Molecule, VE JAM, VEJAM, VE-JAM)
Description:
Junctional adhesion molecule-2 (JAM-2) is a 45kD transmembrane protein a member of the immunoglobulin superfamily otherwise known as CD322. In adult murine tissue CD322 expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:4000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-QRKGYFSKETSFQ, from the internal region of human JAM2/JAMB/CD322 (NP_067042.1).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human JAM2/JAMB/CD322. Sequence Homology: mouse, rat, canine, bovine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Ueki T, Iwasawa K, Ishikawa H, Sawa Y, Expression of junctional adhesion molecules on the human lymphatic endothelium. Microvascular research 2008 Mar 75 (2): 269-78. PMID: 17822725