Technical Data
K0005-07D
Kallikrein 4 (Kallikrein-4, KLK4, AI2A1, ARM1, Enamel Matrix Serine Proteinase 1, EMSP1, EMSP, Kallikrein-like Protein 1, KLK-L1, Kallikrein-related Peptidase 4, MGC116827, MGC116828, Prostase, PSTS, Serine Protease 17, PRSS17)
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In some tissues KLK4 expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the center region of human KLK4 (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human KLK4.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Hart, P.S., et al., J. Med. Genet. 41(7):545-549 (2004). 2.Xi, Z., et al., Cancer Res. 64(7):2365-2370 (2004). 3.Hural, J.A., et al., J. Immunol. 169(1):557-565 (2002). 4.Takayama, T.K., et al., Biochemistry 40(50):15341-15348 (2001). 5.Korkmaz, K.S., et al., DNA Cell Biol. 20(7):435-445 (2001).