Technical Data
K9100-10C
KCNQ1 Potassium Channel (Potassium Voltage-gated channel, KQT-like subfamily, member 1, JLNS1, KCNA8, KCNA9, KQT-like 1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, Voltage-gated Potassium Channel Subunit Kv7.1, WRS)
Description:
KCNQ1 is a member of the K+ channel gene family that when mutated can cause hearing loss. The family is defined by transmembrane domains, single pore-loop K+ channel alpha subunits. KCNQ1 may have an important part in the repolarization of the cardiac action potential in the inner ear, as well as potassium homeostasis. KCNQ1 has been found to be responsible for over 50% of inherited long QT syndrome.

Applications:
Suitable for use in Immunohistochemistry. Other applications have not been tested.

Recommended Dilutions:
Immunohistochemistry: 1:400 detects KCNQ1 in rat brain tissue. May have a tendency to stain vascular tissue.
Optimal dilutions to be determined by the researcher.

Positive Control:
Rat brain tissue

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,k11C246Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Recombinant protein corresponding to human KCNQ1.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity:
Recognizes human KCNQ1. Species crossreactivity: rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.