Technical Data
Luteoreticulin (Griseulin)
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Luteoreticulin is a rare nitrophenyl pyranone closely related to aureothin, neoaureothin and its unusual photoisomers Antibiotics SNF4435C and D. Metabolites within this class have been shown to be potent antitumor agents with pronounced immunosupressive activity and more recently, the ability to reverse multi-drug resistence. The lack of availability of luteoreliculin has hitherto restricted a more intensive investigation of this interesting metabolite with publications relating only to the metabolite's isolation and chemistry.

DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water

CAS Number:

Molecular Formula:

Molecular Weight:
Source: Streptomyces sp.
Purity: >99%
Form: Pale yellow solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. The structure of luteoreticulin, a nitro-containing metabolite of Streptomyces luteoreticuli. Koyama Y. et al. Tetrahedron Lett. 1969, 5, 355. 2. High-performance liquid chromatography comparison of supercritical-fluid extraction and solvent extraction of microbial fermentation products. Cocks S. et al. J Chromatogr A. 1995, 697, 115. 3. Reversal of multidrug resistance by novel nitrophenyl pyrones, SNF4435C and D. Kurosawa K. Jpn. J. Cancer Res. 2001, 92, 1235.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.