Technical Data
Macrophage Inflammatory Protein 3 beta, aa22-98, Recombinant, Human (MIP-3-beta, MIP3B, MIP-3b, Beta Chemokine Exodus-3, C-C Motif Chemokine 19, Chemokine (C-C Motif) Ligand 19, CCL19, CK beta-11, CKb11, Epstein-Barr Virus-induced Molecule 1 Ligand Chemok
Molecular Biology Storage: -20CShipping: Blue Ice
CCL19 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein is involved in immunoregulatory and inflammatory processes. It elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells, CCR7+ effector-memory T-Cells. Recombinant human CCL19 protein, fused to T7-tag at N-terminus, expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Recombinant protein corresponding to aa22-98 of human CCL19 6x his tagged expressed in E.coli.

AA Sequences:

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Source: E.coli
Purity: ~95% (SDS-PAGE).
Concentration: ~0.5mg/ml
Form: Supplied as a liquid in PBS pH 7.4, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Yoshida R, et al. (1997) J Biol Chem. 272(21):13803-9. 2. Robbiani DF, et al. (2000) Cell. 103(5):757-68.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.