Technical Data
M3896-80D
Milbemycin D (Antibiotic B 41D)
1mg
Biochemicals Storage: -20CShipping: Blue Ice
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act on chloride-gated ion channels.

Purity: > 95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO.

Related to: Avermectin B1a, Avermectin B1b, Milbemycin A3, Milbemycin A4, Nemadectin

CAS Number:
77855-81-3

Molecular Formula:
C33H48O7

Molecular Weight:
556.7
Source: Streptomyces hygroscopicus subsp. aureolacrimosus

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Milbemycins, a new family of macrolide antibiotics. Fermentation, isolation and physico-chemical
properties of milbemycins D, E, F, G, and H. Takiguchi Y. et al. J Antibiot. 1983, 36, 502.
2. Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to
GABAergic drugs in cultured chick spinal neurons. Yamazaki J. et al. Comp. Biochem. Physiol. C 1989,
93, 97.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.