Technical Data
MUC5AC (Mucin-5AC, MUC-5AC, Gastric Mucin, Lewis B Blood Group Antigen, LeB, Major Airway Glycoprotein, Mucin-5 Subtype AC, Tracheobronchial, Tracheobronchial Mucin, TBM, MUC5)
MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is involved in epithelial cell proliferation and differentiation in adult airway mucosa and can be used as a marker for hypersecretory disorders. MUC5AC has also been observed in various tumors. For instance it is expressed in primary mucinous ovarian tumors but not in colonic carcinoma metastatic to the ovary, which makes it a useful marker to distinguish the two types of cancer.

Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 1:100
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
50ug-20CBlue IceHumanMouse
As reported
Mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification).
Supplied as a liquid in PBS, 0.05% sodium azide.
Recognizes human MUC5AC.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.