Technical Data
M5010-01
Mupirocin ((2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid, 8-Carboxyoctyl Ester, Pseudomonic Acid A, trans-pseudomonic Acid, BRL-4910A, Bactroban, Turixin)
25mg
Biochemicals Storage: -20CShipping: Blue Ice
Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.

Solubility:
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
12650-69-0

Molecular Formula:
C26H44O9

Molecular Weight:
500.6
Source: Pseudomonas fluorescens
Purity: ~95% (HPLC)
Form: Supplied as a white solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller A.T. et al., Nature 1971, 234, 416. 2. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Sutherland R., Antimicrob Agents Chemother. 1985, 27, 495. 3. Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Hughes J. & Mellows G., Biochem. J. 1978, 176, 305.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.