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Technical Data |
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M5010-01 |
Mupirocin ((2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid, 8-Carboxyoctyl Ester, Pseudomonic Acid A, trans-pseudomonic Acid, BRL-4910A, Bactroban, Turixin) |
25mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase. Source: Pseudomonas fluorescens MST-AS5326 Apperance: White solid Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility Storage and Stability: May be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. CAS Number: 12650-69-0 Molecular Formula: C26H44O9 Molecular Weight: 500.6 |
Source: Pseudomonas fluorescens MST-AS5326 Purity: ~95% Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller A.T. et al., Nature 1971, 234, 416. 2. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Sutherland R., Antimicrob Agents Chemother. 1985, 27, 495. 3. Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Hughes J. & Mellows G., Biochem. J. 1978, 176, 305.
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