Technical Data
P1775-30F
ADCYAP1R1, NT (Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor, PACAP Type I Receptor, PACAP-R-1, PACAP-R1)
Description:
The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525aa protein with a signal peptide of 77aa encoded by nt 74-304 and the second (nt 245-247) initiates a 468aa protein with a signal peptide of 20aa encoded by nt 245-304. The efficiency of these two start codons is not known.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 5-7ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to human ADCYAP1R1.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes human ADCYAP1R1. Species sequence homology: mouse (22%) and rat (22%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.