Description:
Pancreas Polypeptide is located in the pancreatic islets and in the exocrine pancreas. Useful for the diagnosis of tumors of pancreatic origin and of bronchial and rectal carcinoids.
Applications:
Suitable for use in ELISA, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:
Immunohistochemistry (frozen and paraffin, no pretreatment necessary): 1:50-1:100
Immunocytochemistry: 1:50-1:100
ELISA: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Recommended Positive Control:
Pancreas
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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| Type | Isotype | Clone | Grade |
|---|
| Pab | IgG | | Serum |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 250ul | | -20°C | Blue Ice | Bovine | Rabbit |
|
| Concentration: |
| Not determined |
| Immunogen: |
| Bovine pancreas polypeptide (BSA). |
| Purity: |
| Serum |
| Form |
| Supplied as a liquid in PBS, 1% BSA, 0.1% sodium azide. |
| Specificity: |
| Recognizes bovine Pancreas Polypeptide. Species Crossreactivity: Human, porcine, hamster, rat. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Kohnert KD et al: Islet neuronal abnormalities associated with impaired insulin secretion in type 2 diabetes in the Chinese hamster. Regul Pept 82, 71-79 (1999). Myrsén U et al: Beta cells are important for islet innervation: evidence from purified rat islet-cell grafts. Diabetologia 39, 54-59 (1996). 2. Myrsén U et al: Neuropeptide Y is expressed in islet somatostatin cells of the hamster pancreas: a combined immunocytochemical and in situ hybridization study. Regul Pept 57, 65-76 (1995). 3. Böttcher G et al: Peptide YY in the mammalian pancreas: immunocytochemical localization and immunochemical characterization. Regul Pept 43, 115-130 (1993). 4. El-Salhy M et al: Peptidergic innervation and endocrine cells in the human liver. Scand J Gastroenterol 28, 809- 815 (1993).
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