Pancreas Polypeptide is located in the pancreatic islets and in the exocrine pancreas. Useful for the diagnosis of tumors of pancreatic origin and of bronchial and rectal carcinoids.
Suitable for use in ELISA, Immunocytochemistry and Immunohistochemistry. Other applications not tested.
Immunohistochemistry (frozen and paraffin, no pretreatment necessary): 1:50-1:100
Optimal dilutions to be determined by the researcher.
Recommended Positive Control:
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
| Not determined|
|Bovine pancreas polypeptide, conjugated to BSA|
|Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide.|
|Recognizes bovine Pancreas Polypeptide. Species Crossreactivity: Human, porcine, hamster, rat.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. Kohnert KD et al: Islet neuronal abnormalities associated with impaired insulin secretion in type 2 diabetes in the Chinese hamster. Regul Pept 82, 71-79 (1999). Myrsén U et al: Beta cells are important for islet innervation: evidence from purified rat islet-cell grafts. Diabetologia 39, 54-59 (1996). 2. Myrsén U et al: Neuropeptide Y is expressed in islet somatostatin cells of the hamster pancreas: a combined immunocytochemical and in situ hybridization study. Regul Pept 57, 65-76 (1995). 3. Böttcher G et al: Peptide YY in the mammalian pancreas: immunocytochemical localization and immunochemical characterization. Regul Pept 43, 115-130 (1993). 4. El-Salhy M et al: Peptidergic innervation and endocrine cells in the human liver. Scand J Gastroenterol 28, 809- 815 (1993).|