Technical Data
Phosphodiesterase 4D (Phosphodiesterase 4D cAMP Specific, PDE4D, cAMP Specific 3' 5' Cyclic Phosphodiesterase 4D, cAMP Specific Phosphodiesterase 4D, cAMP Specific Phosphodiesterase PDE4D, Cyclic AMP Phosphodiesterase, Dunce-like Phosphodiesterase E3, DPD
The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003).[supplied by OMIM]

Positive Control: Rat Brain lysate

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
100ug-20CBlue IceHumanGoat
Synthetic peptide, HVNNFPFRRHS-C, representing the N Terminus of the human protein according to AAA97892.1. Homology: Human, Rat Epitope: HVNNFPFRRHS-C
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
Species Crossreactivity: Human and rat. Other species not tested.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Staton JM, Sayer MS, Hankey GJ, Attia J, Thakkinstian A, Yi Q, Cole VJ, Baker R, Eikelboom JW. Association between phosphodiesterase 4D gene and ischaemic stroke. J Neurol Neurosurg Psychiatry. 2006 Sep;77(9):1067-9. PMID: 16914755