Technical Data
Phosphodiesterase 1C (Phosphodiesterase 1C Calmodulin Dependent 70kDa, Phosphodiesterase 1C Calmodulin-dependent, PDE1C, Calcium/calmodulin-dependent 3'5'-cyclic Nucleotide Phosphodiesterase 1C, Cam-PDE-1C, hCAM3, hCAM-3, HSPDE1C1A, Human 3'5' Cyclic Nucl
Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.

Positive Control: Thyroid

Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabAffinity Purified
50ug-20CBlue IceHumanRabbit
Synthetic peptide - KLH conjugated (exact sequence is proprietary information). Epitope: C-terminal domain of human
Purified by peptide immunoaffinity chromatography.
Supplied as a liquid in PBS, pH 7.2.
This antibody is specific to the human PDE1C protein. Species Crossreactivity: Human. Other species not yet tested.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.