Technical Data
P4190-20
Pimozide, Stat5 Inhibitor (1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one)
50mg
250mg
Biochemicals Storage: 4CShipping: Blue Ice
Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

Molecular Weight:
~461.55

Solubility:
DMSO (100mM)

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
2062-78-4

Molecular Formula:
C28H29F2N3O

Molecular Weight:
461.55
Purity: ~98% (TLC)
Concentration: Not determined
Form: Supplied as a white solid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Nelson, E.A., et al. (2011). Blood 117, 3421-3429.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.