Technical Data
S1001-15P
Serotonin Receptor 1F (5-Hydroxytryptamine 1F Receptor, 5-Hydroxytryptamine (Serotonin) Receptor 1F, 5HT1F Receptor, 5HT1F, 5-HT1F, 5-HT-1F, 5-Hydroxytryptamine (Serotonin) Receptor 1E beta, HGNC:5292, HTR1EB, HTR1EL, HTR1F, MR77, Serotonin Receptor 1E be
Description:
5HT1F, a Serotonin Receptor, is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 6.5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to 3rd cytoplasmic domain of human HTR1F (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes human HTF1F. Species sequence homology: Mouse (75/81%) and rat (81/88%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.