Technical Data
S1012-98B
EAT2A/EAT2B (Sh2d1b, SH2 domain protein 1B [Mus musculus], MGI:1349420, EAT-2, EAT-2A, Eat2, Eat2a, EWS/FLI1 activated transcript 2, Sh2d1b, SH2 domain protein 1B2, EAT-2B, Eat2b, Sh2d1c, EAT-2-related transducer)
Description:
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM]

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-ELNVYENTDEEYVD from the C Terminus of EAT2A/EAT2B (NP_036139.2).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes EAT2A/EAT2B. Sequence Homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Roncagalli R, Taylor JE, Zhang S, Shi X, Chen R, Cruz-Munoz ME, Yin L, Latour S, Veillette A. Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Nat Immunol. 2005 Oct;6(10):1002-10. PMID: 16127454.