Technical Data
SMARCB1 (SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily B Member 1, BAF47, hSNF5, Integrase Interactor 1 Protein, INI1, RDT, Sfh1p, SNF5, SNF5L1, Snr1, Sucrose Nonfermenting Yeast Homolog-like 1, SWI/SNF Complex Compone
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.

Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabAffinity Purified
100ug-20CBlue IceHumanRabbit
As reported
Antibody was affinity purified using an epitope specific to SMARCB1/SNF5 immobilized on solid support. The epitope recognized by this antibody maps to a region between residue 75 and 125 of human SWI/SNF related, matrix associated, actin dependent regulat
Purified by immunoaffinity chromatography.
Tris-citrate/phosphate buffer, pH 7 to 8
Species Crossreactivity: Human and Mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.