Technical Data
STAT 1 (Signal Transducer and Activator of Transcription 1, Signal Transducer and Activator of Transcription 1 91kDa, Signal Transducer and Activator of Transcription 1 alpha/beta, STAT1, STAT-1, DKFZp686B04100, ISGF-3, STAT 91, STAT91, Transcription Fact
STAT1 is a member of the STAT family of cytoplasmic transcription factors that mediate cytokine, growth factor and hormone receptor signal transduction. STAT is associated with type I and II interferon signaling. Phosphorylation of STAT1a at Y701 leads to dimerization and translocation to the nucleus to activate gene transcription. Human STAT1 shows 93% and 94% aa identity with mouse and rat STAT1, respectively, over the region used as an immunogen. This region is identical between isoforms STAT1a (91kD) and STAT1b (84kD).

Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
MabIgG2b11D110Affinity Purified
100ug-20CBlue IceHumanMouse
Not determined
Recombinant corresponding to Ala687Val750 in STAT1 expressed in E. coli (P42224).
Purified by Protein A/G affinity chromatography.
Supplied as a lyophilized powder in PBS with Trehalose. Reconstitute with sterile PBS.
Recognizes human STAT1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.