Technical Data
S8000-11
Substance P (NK, Neurokinin)
Description:
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Application(s): Immunohistochemistry: 1:5,000–1:10,000 (18–24 hour incubation) on formalin, Bouin’s or Zamboni’s fixed tissue. Will react on paraffin embedded tissue. RIA: 1:10,000 80% binding detects at least 5 pg/ml.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Substance P
Purity:
Neat serum.
Form
Liquid with 0.1% sodium azide
Specificity:
Substance P Species Reactivity: Human, rat and mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Brain Research (1986) 377:199–203. Biology of Reproduction (1985) 33:471–476. Life Sciences (1985) 37:1627–1632.