		Technical Data
S9108-03E	Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38)

Description:
Synaptophysin is a glycoprotein located in the membrane of synaptic vesicles that is ubiquitously expressed in all neurons. It is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors.This antibody has been used to detect the following neuronal and adrenal tumors: pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas; neuroendocrine tumors of epithelial origin; pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids and medullary carcinoma of the thyroid.

Applications:
Suitable for use in Immunohistochemistry (frozen and paraffin) and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1	10F486	Affinity Purified

Size		Storage	Shipping	Source	Host
25ug		-20°C	Blue Ice	Human	Mouse

Concentration:

~0.05mg/ml

Immunogen:

Synaptophysin presynaptic vesicles.

Purity:

Purified by Protein A affinity chromatography.

Form

Supplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide.

Specificity:

Recognizes human Synaptophysin. Species crossreactivity: rat, mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.