Technical Data
T1041-04E
TAU (S720) (Microtubule-associated Protein Tau, Neurofibrillary Tangle Protein, Paired Helical Filament-Tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT)
Description:
MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 699-728 from human TAU, UniProt Accession #P10636. Species sequence homology: mouse, rat, bovine
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human TAU.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.McCulloch,C.C., Hum. Genet. 123(3), 257-265 (2008). 2.Mateo,I., Dement Geriatr Cogn Disord 25(4), 317-320 (2008). 3.Beck,J., Brain 131(PT 3), 706-720 (2008).