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Technical Data |
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T3662-50 |
TGR5 Receptor Agonist (3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethylisoxazole-4-carboxamide) |
5mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Cell-permeable, small molecule agonist of TGR5 G-protein coupled receptor. This agonist has shown to increase glucagon like peptide-1 (GLP-1) secretion from primary intestinal cells. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Formula: C18H14Cl2N2O2 Molecular Weight: 361.22 |
Purity: ~98% (HPLC) Form: Supplied as a crystalline solid. Reconstitute with DMSO. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Evans, K.A., et al. (2009). J. Med. Chem. 52, 7962-7965.
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