Technical Data
T8464-40A
TRIM2 (Tripartite Motif-containing 2, Tripartite Motif Containing 2, KIAA0517, Ring Finger Protein 86, RNF86)
Description:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.

Applications:
Suitable for use in ELISA and Western Blot. Other applications have not been tested.

Recommended Dilutions:
Peptide ELISA Titer: 1:16,000
Western Blot: 0.5-2ug/ml ~80+85kD bands observed in Rat Brain lysates (calculated MW of 81.5kD according to Human NP_001123539.1, 84.4 according to Human NP_056086.2 and 83.3 according to Rat NP_001102022.1).
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to DSGNHCFKVYRYLQ, from the C Terminus of human TRIM2 (NP_056086.2; NP_001123539.1).
Purity:
Purified by peptide affinity chromatography.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:
Recognizes TRIM2. This antibody is expected to recognise both reported isoforms. Species crossreactivity: rat. Species sequence homology: human, mouse, canine, bovine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A.The tripartite motif family identifies cell compartments.
EMBO J. 2001 May 1;20(9):2140-51.