HSV Diagnosis
Upon primary infection by a HSV virus, the sensory neurons are colonised and the infection may reactivate causing recurrent sub-clinical or clinical infection. To diagnose HSV infections, serological methods often use viral lysates to raise antibodies and develop immunoassays. However, viral lysate assays are unable to differentiate HSV-1 infections from HSV-2 infections due to the high degree of antigenic similarity between the viruses. Moreover, given that HSV-1 infection is extremely common in adults, such assays are unable to detect HSV-2 infection with any confidence.
HSV gG2s
HSV gG2 protein shares very little sequence similarity between the two Herpes Simplex viruses. Therefore, gG2 protein can be used to develop specific HSV-2 assays to determine the HSV-2 status of expectant mothers, and allows clinicians to make appropriate therapeutic interventions for infected newborns.
Our HSV-2 gG2 protein is a highly purified product prepared from virus cultivated in mammalian cells, offering significant advantages over other partially purified native antigens, or bacterial expressed recombinant antigens that are not glycosylated. Tests have also shown excellent performance in assays for the distinguishing between HSV1 and HSV2-infected patients. We can also provide HSV-2 gG2 in bulk quantities for use in IVD manufacture or other applications.
| Cat # | Product Name |
|---|---|
| 518160 | Herpes Simplex Virus gG2, Strain G |
We accept the following payment methods as well as pay-by-invoice.
