Semaphorin-7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage. It is an 80kD glycoprotein expressed on activated lymphocytes and erythrocytes. It may play an important role in the nervous system and in modulating immune function. It is expressed in placenta, testis, ovary, spleen, brain, spinal cord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.
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