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030776 Mouse Anti-APCS (APCS, PTX2, Serum amyloid P-component, 9.5S alpha-1-glycoprotein, Serum amyloid P-component(1-203))

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
P02743
Isotype
IgG2a
Clone Number
342CT9.4.7
Grade
Ascites
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001630.1;
Gene ID
325
Gene #
APCS
Shipping Temp
Blue Ice
Storage Temp
-20°C
APCS, PTX2, Serum amyloid P-component, 9.5S alpha-1-glycoprotein, Serum amyloid P-component(1-203)

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Applications
Suitable for use in Western Blot, ELISA.
Recommended Dilution
ELISA: 1:1000 Western Blot: 1:500~4000
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified His-tagged APCS protein (fragment).
Form
Supplied as a liquid, 0.09% sodium azide.
Purity
Ascites
Specificity
Human
References
Song, Z., et al. Atherosclerosis 211(1):90-95(2010)|Davila, S., et al. Genes Immun. 11(3):232-238(2010)|McGeachie, M., et al. Circulation 120(24):2448-2454(2009)|Lu, J., et al. Nature 456(7224):989-992(2008)|Verwey, N.A., et al. Dement Geriatr Cogn Disord 26(6):522-527(2008)
USBio References
No references available
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