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031142-PE Mouse Anti-MX1 (MX1, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, Interferon-induced GTP-binding protein Mx1, N-terminally processed) (PE)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
P20591
Conjugate
PE
Isotype
IgG2b
Clone Number
474CT4.1.5
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_001138397.1
Gene ID
4599
Gene #
MX1
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
MX1, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, Interferon-induced GTP-binding protein Mx1, N-terminally processed

In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene.

Applications
Suitable for use in Western Blot and FLISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 617-646 of human MX1, UniProt Accession #P20591. Species Sequence Homology: porcine
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human MX1.
References
1. Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010). 2. van der Voort, L.F., et al. Neurology 75(14):1228-1233(2010). 3. Ching, J.C., et al. J. Infect. Dis. 201(12):1899-1908(2010). 4. Zhijian, Y., et al. Virol. J. 7, 278 (2010). 5. Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)
USBio References
No references available
Conjugates
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