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031477 Rabbit Anti-ABCC3, ID (ABCC3, CMOAT2, MLP2, MRP3, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_003777.2; NP_001137542.1; O15438
Gene ID
8714
Gene #
ABCC3
Shipping Temp
Blue Ice
Storage Temp
-20°C
ABCC3, CMOAT2, MLP2, MRP3, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ABCC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 906-933 amino acids from the Central region of human ABCC3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Hoffman, A.D., et al. Protein J. 29(5):373-379(2010)|Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)
USBio References
No references available
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