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031698 Rabbit Anti-AGL, CT (AGL, GDE, Glycogen debranching enzyme, Glycogen debrancher, 4-alpha-glucanotransferase, Oligo-1,4-1,4-glucantransferase, Amylo-alpha-1,6-glucosidase, Dextrin 6-alpha-D-glucosidase)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P35573
Isotype
IgG
Grade
Purified
Applications
E IF WB
Crossreactivity
Hu
Gene ID
178
Gene #
AGL
Shipping Temp
Blue Ice
Storage Temp
-20°C
AGL, GDE, Glycogen debranching enzyme, Glycogen debrancher, 4-alpha-glucanotransferase, Oligo-1,4-1,4-glucantransferase, Amylo-alpha-1,6-glucosidase, Dextrin 6-alpha-D-glucosidase

AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.

Applications
Suitable for use in Western Blot, Immunofluorescence, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot1:100-500 Immunofluorescence: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1487~1516 amino acids from the C-terminal region of human AGL.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human
References
Horinishi, A., et al., J. Hum. Genet. 47(2):55-59 (2002).|Bao, Y., et al., Genomics 38(2):155-165 (1996).|Yang, B.Z., et al., J. Biol. Chem. 267(13):9294-9299 (1992).|Yang-Feng, T.L., et al., Genomics 13(4):931-934 (1992).|Bao, Y., et al., Gene 197 (1-2), 389-398 (1997).
USBio References
No references available
Conjugates
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