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031738 Rabbit Anti-AKIRIN2, CT (AKIRIN2, C6orf166, Akirin-2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q53H80
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_060534.1
Gene ID
55122
Gene #
AKIRIN2
Shipping Temp
Blue Ice
Storage Temp
-20°C
AKIRIN2, C6orf166, Akirin-2

Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AKIRIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human AKIRIN2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Komiya, Y., et al. J. Biol. Chem. 283(27):18753-18764(2008)|Goto, A., et al. Nat. Immunol. 9(1):97-104(2008)|Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :|Vasan, R.S., et al. BMC Med. Genet. 8 SUPPL 1, S2 (2007) :|Olsen, J.V., et al. Cell 127(3):635-648(2006)
USBio References
No references available
Conjugates
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