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033178 Rabbit Anti-CAPN11, ID (CAPN11, Calpain-11, Calcium-activated neutral proteinase 11)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9UMQ6
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_008989.2
Gene ID
11131
Gene #
CAPN11
Shipping Temp
Blue Ice
Storage Temp
-20°C
CAPN11, Calpain-11, Calcium-activated neutral proteinase 11

Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CAPN11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-438 amino acids from the Central region of human CAPN11.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Ben-Aharon, I., et al. Mol. Reprod. Dev. 73(6):767-773(2006)|Dear, T.N., et al. Genomics 59(2):243-247(1999)|Rojas, F.J., et al. Mol. Hum. Reprod. 5(6):520-526(1999)|Saido, T.C., et al. FASEB J. 8(11):814-822(1994)|Melloni, E., et al. Trends Neurosci. 12(11):438-444(1989)
USBio References
No references available
Conjugates
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