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033892 Rabbit Anti-CHTF18, CT (CHTF18, C16orf41, CTF18, Chromosome transmission fidelity protein 18 homolog, CHL12)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8WVB6
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_071375.1
Gene ID
63922
Gene #
CHTF18
Shipping Temp
Blue Ice
Storage Temp
-20°C
CHTF18, C16orf41, CTF18, Chromosome transmission fidelity protein 18 homolog, CHL12

CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 913-943 amino acids from the C-terminal region of human CHTF18.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Murakami, T., et al. J. Biol. Chem. 285(45):34608-34615(2010)|Farina, A., et al. J. Biol. Chem. 283(30):20925-20936(2008)|Shiomi, Y., et al. J. Biol. Chem. 282(29):20906-20914(2007)|Matsuoka, S., et al. Science 316(5828):1160-1166(2007)|Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
USBio References
No references available
Conjugates
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