COL17A1, ID

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9UMD9

Conjugate

FITC

Isotype

IgG

Grade

Affinity Purified

Applications

FLISA WB

Crossreactivity

Gene ID

1308

Gene #

COL17A1

Shipping Temp

Blue Ice

Storage Temp

-20°C

Notes

Preservative Free

COL17A1, BP180, BPAG2, Collagen alpha-1(XVII) chain, 180kD bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120kD linear IgA disease antigen, 120kD linear IgA dermatosis antigen, Linear IgA disease antigen 1, 97kD linear IgA disease antigen, 97kD linear IgA bullous dermatosis antigen, Linear IgA bullous disease antigen of 97kD

COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.

Applications

Suitable for use in FLISA and Western Blot. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested.

Recommended Dilutions

Optimal dilutions to be determined by the researcher.

Storage and Stability

Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa475-504 in the central region of human COL17A1.

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human COL17A1.

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Clone Type

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Source

Swiss Prot

Conjugate

Isotype

Grade

Applications

Crossreactivity

Gene ID

Gene #

Shipping Temp

Storage Temp

Notes

References

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Conjugates

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