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034197 Rabbit Anti-CRABP1, CT (CRABP1, RBP5, Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P29762
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_004369.1
Gene ID
1381
Gene #
CRABP1
Shipping Temp
Blue Ice
Storage Temp
-20°C
CRABP1, RBP5, Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I

This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CRABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the C-terminal region of human CRABP1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
References
Tang, X.H., et al. Exp. Cell Res. 314(1):38-51(2008)|Uhrig, M., et al. BMC Med 6, 38 (2008) :|Guidez, F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(47):18694-18699(2007)|Tanaka, K., et al. Oncogene 26(44):6456-6468(2007)|Wu, Q., et al. Mol. Cancer 6, 45 (2007) :|Flagiello, D., et al. Cytogenet. Cell Genet. 76 (1-2), 17-18 (1997) :|Liu, W., et al. Biochem. Biophys. Res. Commun. 229(3):922-929(1996)|Eller, M.S., et al. Exp. Cell Res. 198(2):328-336(1992)|Astrom, A., et al. J. Biol. Chem. 266(26):17662-17666(1991)|Ong, D.E. Arch Dermatol 123 (12), 1693-1695A (1987) :
USBio References
No references available
Conjugates
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