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035067 Rabbit Anti-ENAH, CT (ENAH, MENA, Protein enabled homolog)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8N8S7
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_060682.2
Gene ID
55740
Gene #
ENAH
Shipping Temp
Blue Ice
Storage Temp
-20°C
ENAH, MENA, Protein enabled homolog

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ENAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-475 amino acids from the C-terminal region of human ENAH.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)|Hahn, W.H., et al. Exp. Mol. Med. 41(11):793-801(2009)|Gurzu, S., et al. Rom J Morphol Embryol 50(2):213-216(2009)|Higashi, M., et al. PLoS ONE 4 (3), E4765 (2009) :
USBio References
No references available
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