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035211-Biotin Rabbit Anti-ERLIN2, CT (ERLIN2, C8orf2, SPFH2, Erlin-2, Endoplasmic reticulum lipid raft-associated protein 2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (Biotin)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
Biotin
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001003790.1; O94905
Gene ID
11160
Gene #
ERLIN2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
ERLIN2, C8orf2, SPFH2, Erlin-2, Endoplasmic reticulum lipid raft-associated protein 2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 307-333 in the C-terminal region of human ERLIN2, UniProt Accession #O94905.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ERLIN2.
References
Wang, Y., et al. Biochim. Biophys. Acta 1793(11):1710-1718(2009) Pearce, M.M., et al. J. Biol. Chem. 284(16):10433-10445(2009) Pearce, M.M., et al. J. Biol. Chem. 282(28):20104-20115(2007) Browman, D.T., et al. J. Cell. Sci. 119 (PT 15), 3149-3160 (2006) : Garcia, M.J., et al. Oncogene 24(33):5235-5245(2005)
USBio References
No references available
Conjugates
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