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037171 Rabbit Anti-IZUM1, NT (IZUMO1, Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, Sperm-specific protein izumo)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8IYV9
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_872381.2
Gene ID
284359
Gene #
IZUMO1
Shipping Temp
Blue Ice
Storage Temp
-20°C
IZUMO1, Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, Sperm-specific protein izumo

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 77-105 from the N-terminal region of human IZUM1
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human IZUM1
References
1. Ellerman, D.A., et al. Mol. Reprod. Dev. 76(12):1188-1199(2009). 2. Inoue, N., et al. Biochem. Biophys. Res. Commun. 377(3):910-914(2008). 3. Granados-Gonzalez, V., et al. Fertil. Steril. 90(4):1246-1248(2008). 4. Yatsenko, A.N., et al. Hum. Mol. Genet. 15(23):3411-3419(2006). 5. Inoue, N., et al. Nature 434(7030):234-238(2005).
USBio References
No references available
Conjugates
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