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038114 Rabbit Anti-MAP1LC3B, phosphorylated (T93/Y99) (APG8b, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 beta)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9GZQ8
Isotype
IgG
Grade
Affinity Purified
Applications
DB E
Crossreactivity
Hu
Accession #
NP_073729
Gene ID
81631
Gene #
MAP1LC3B
Shipping Temp
Blue Ice
Storage Temp
-20°C
APG8b, MAP1ALC3, Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 beta

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Applications
Suitable for use in Dot Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Dot blot 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Phospho-APG8b (MAP1LC3B)-T93/Y99 Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding T93/Y99 of human APG8b.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Rouschop, K.M., et al. J. Clin. Invest. 120(1):127-141(2010)|Kirkin, V., et al. Mol. Cell 33(4):505-516(2009)|Othman, E.Q., et al. J. Clin. Lab. Anal. 23(4):249-258(2009)|Liu, Q., et al. Ai Zheng 27(1):25-29(2008)|Komatsu, M., et al. Cell 131(6):1149-1163(2007)
USBio References
No references available
Conjugates
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