PI3KCD, NT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

O00329; O35904

Isotype

IgG

Grade

Purified

Applications

E IF IHC WB

Crossreactivity

Gene ID

5293

Gene #

PIK3CD

Shipping Temp

Blue Ice

Storage Temp

-20°C

PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110kD catalytic subunit delta

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha , p110-beta, and p110-gamma. p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras.

Applications

Suitable for use in Western Blot, Immunohistochemistry, ELISA and Immunofluorescence. Other applications not tested.

Recommended Dilution

Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 85-114 in the N-terminal region of human PI3KCD. Species sequence homology: mouse.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by ammonium sulfate precipitation.

Specificity

Recognizes human PI3KCD.

References

1. Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003). 2. Sadhu, C., et al., J. Immunol. 170(5):2647-2654 (2003). 3. Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002). 4. Cook, J.A., et al., J. Immunol. 169(1):254-260 (2002). 5. Zauli, G., et al., FASEB J. 15(2):483-491 (2001).

USBio References

No references available

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039996 Rabbit Anti-PI3KCD, NT (PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110kD catalytic subunit delta)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Gene ID

Gene #

Shipping Temp

Storage Temp

PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110kD catalytic subunit delta

References

USBio References

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