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041744 Rabbit Anti-SIKE, CT (SIKE1, SIKE, Suppressor of IKBKE 1, Suppressor of IKK-epsilon)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9BRV8
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_001095866.1; NP_079349.2
Gene ID
80143
Gene #
SIKE1
Shipping Temp
Blue Ice
Storage Temp
-20°C
SIKE1, SIKE, Suppressor of IKBKE 1, Suppressor of IKK-epsilon

SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SIKE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the C-terminal region of human SIKE.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Goudreault, M., et al. Mol. Cell Proteomics 8(1):157-171(2009)|Huang, J., et al. EMBO J. 24(23):4018-4028(2005)
USBio References
No references available
Conjugates
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