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044587 Rat Anti-BAFF-R (BAFF Receptor, BR3, BlySR3, CD268, TNFRSF13C)

Specifications
References
Clone Type
Monoclonal
Host
Rat
Source
Mouse
Isotype
IgG2b
Clone Number
9B9
Grade
Affinity Purified
Applications
FC
Crossreactivity
Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
BAFF Receptor, BR3, BlySR3, CD268, TNFRSF13C

Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.

Applications
Suitable for use in Functional Applications and Flow Cytometry. Other applications not tested.
Recommended Dilution
Functional Application: Depletion of B cells in vivo. Optimal dilutions to be determined by researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Y3 cells transfected with mouse BAFF-R.
Form
Supplied as a liquid in PBS. No preservative added.
Purity
Purified by Protein G affinity chromatography from concentrated hybridoma tissue culture supernatant. Endotoxin: <0.01EU/ug (LAL test; Lonza).
Specificity
Recognizes mouse BAFF-R.
References
1. Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells: M. Rauch, et al.; PLoS ONE 4, e5456 (2009)|2. BAFF-R expression correlates with positive selection of immature B cells: R. Tussiwand, et al.; Eur. J. Immunol. (Epub ahead of print) (2011)
USBio References
No references available
Conjugates
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