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134300 Mouse Anti-TCIRG1 (T-cell Immune Regulator 1, ATP6N1C, ATP6V0A3, V-type Proton ATPase 116kD Subunit a Isoform 3, V-ATPase 116kD Isoform a3, Osteoclastic Proton Pump 116kD Subunit, OC-116kD, OC116, T-cell Immune Response cDNA7 Protein, TIRC7, Vacuolar Proton Translocating ATPase 116kD Subunit a Isoform 3)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a,k
Clone Number
6H3
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
BC018133, AAH18133
Shipping Temp
Blue Ice
Storage Temp
-20°C
a3, Atp6i, OPTB1, Stv1, Vph1

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
QLHQLQLHAAVLRQGHEPQLAAAHTDGASERTPLLQAPGGPHQDLRVNFVAGAVEPHKAPALERLLWRACRGFLIASFRELEQPLEHPVTGEPATWMTFL
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant corresponding to aa121-220 from TCIRG1 (AAH18133) with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in PBS, pH 7.2.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human TCIRG1.
References
1. A specific subtype of osteoclasts secretes factors inducing nodule formation by osteoblasts. Henriksen K, Andreassen KV, Thudium CS, Gudmann KN, Moscatelli I, Cruger-Hansen CE, Schulz AS, Dziegiel MH, Richter J, Karsdal MA, Neutzsky-Wulff AV.Bone. 2012 Jun 19;51(3):353-361. 2. Impaired gastric acidification negatively affects calcium homeostasis and bone mass. Schinke T, Schilling AF, Baranowsky A, Seitz S, Marshall RP, Linn T, Blaeker M, Huebner AK, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil FT, Del Fattore A, Frattini A, Streichert T, Pueschel K, Villa A, Debatin KM, RuegNat Med. 2009 Jun;15(6):674-81. 3. Differential Localization of Vacuolar H+-ATPases Containing a1, a2, a3, or a4 (ATP6V0A1-4) Subunit Isoforms Along the Nephron. Schulz N, Dave MH, Stehberger PA, Chau T, Wagner CA.Cell Physiol Biochem. 2007;20(1-4):109-20.
USBio References
No references available
Conjugates
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