(EC 3.1.3.16, PP 1G, PP-1G, PP1G, PP1G_HUMAN, PP1gamma, PPP 1G, PPP1CC, PPP1CC protein, PPP1G, Protein phosphatase 1 catalytic subunit gamma isoform, Protein phosphatase 1C catalytic subunit, Protein phosphatase 1C subunit, Protein phosphatase 2C gamma isoform, Serine/threonine phosphatase 1 gamma, Serine/threonine protein phosphatase PP1 gamma catalytic subunit, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit)
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:500 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified recombinant human PPP1CC protein fragments expressed in E. coli.
Form
Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4,150mM NaCl, 0.2% sodium azide, 0.1mg/ml BSA, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes endogenous levels of PPP1CC. Does not cross-react with related proteins. Species Crossreactivity: human
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