Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity(ED50 = 70nM) relative to kringles 1-4(ED50 = 135nM).

P00747

PLG

Suitable for use in FLISA, Western Blot and Immunohistochemistry (Paraffin).

Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

E. coli-derived human Angiostatin K1-3 recombinant protein (Position: C103-C352).

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.

Purified by immunoaffinity chromatography.

Recognizes human Angiostatin K1-3. No crossreactivity with other proteins.