IL-29 (Interleukin-29) is a secreted cytokine with immunomodulatory activity. It may play a role in viral immunity. It up-regulates MHC class I expression. IL-29 is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Its induction is by viral infections or double stranded RNA. IL-29 is ideal for investigators involved in immunology research.
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